Names of sedating antihistamines
In 2014, antihistamines such as desloratadine were found to be effective as adjuvants to standardized treatment of acne due to their anti-inflammatory properties and their ability to suppress sebum production.
Some of the main side effects of antihistamines include: If you take an antihistamine that causes drowsiness, do so before bedtime.
Histamine produces increased vascular permeability, causing fluid to escape from capillaries into tissues, which leads to the classic symptoms of an allergic reaction — a runny nose and watery eyes. Antihistamines suppress the histamine-induced wheal response (swelling) and flare response (vasodilation) by blocking the binding of histamine to its receptors or reducing histamine receptor activity on nerves, vascular smooth muscle, glandular cells, endothelium, and mast cells.
Itching, sneezing, and inflammatory responses are suppressed by antihistamines that act on H1-receptors.
When your body comes into contact with whatever your allergy trigger is -- pollen, ragweed, pet dander, or dust mites, for example -- it makes chemicals called histamines.
They cause the tissue in your nose to swell (making it stuffy), your nose and eyes to run, and your eyes, nose, and sometimes mouth to itch.